Fittings for Columns

Several different types of fittings are available for connecting tubing to our chromatography columns. These include plain tubing fittings, On/Off valves, Metering valves, Valves with several fittings, and tubing fittings for the vent port.

In addition to the fittings listed here, PTFE fittings that connect 2 or more pieces of tubing are also available. They are described here


The On/Off Valve is used to stop or allow flow from the column. It is not useful for controlling the rate of flow; a metering valve should be used for that purpose.

An On/Off valve is usually placed at the column outlet when doing gravity-flow chromatography. Closing a valve at the column outlet will stop the flow and yet keep the column packing wet even if a leak were to develop. For medium-term storage of a packed column two valves are usually used, one at the column inlet and one at the outlet. This also helps to keep the column packing wet.

One end of these On/Off valves screws into the column endplate, replacing the existing tubing fitting. The other end of the valve has a tubing fitting. Valves which attach to 4 different sizes of tubing are available. The only wetted material in these valves is PTFE (THE white fluoropolymer).

On/Off Valve Availability
Part No.DescriptionPrice
124414On/Off valve for connecting 1/16" OD tubing to column.159.00
124420On/Off valve for connecting 1/8" OD tubing to column.146.00
124416On/Off valve for connecting 3/16" OD tubing to column.146.00
124426On/Off valve for connecting 1/4" OD tubing to column.181.00



The Metering Valve adds a flow control feature to the on/off valve.

A metering valve placed at the column outlet allows you to control the rate of flow when using gravity flow. We recommend placing this valve at the outlet rather than the inlet to minimize any affect a small leak would have on the column packing. (If the valve were at the inlet air might be drawn into the column. With the valve at the outlet the column will be under positive pressure and any leak will be fluid leaving the column and not air entering it.)

As with the on/off valves, these screw into the column endplate replacing the existing tubing fitting. The other end of the valve has a tubing fitting. The only wetted materials in these valves are PTFE and Kel-F.

A combination 3-way valve and metering valve is available as a Stream Splitting valve.

Metering Valve Availability
Part No.DescriptionPrice
124432Metering valve for connecting 1/8" OD tubing to column.226.00



Various Multi-Port Valves are available for direct connection to the column endplates. These valves replace the tubing connector and are themselves equipped with tubing fittings.

The 3-Port T-Bore Valve is used for mixing, solvent selection, and flow diversion. It has 2 tubing fittings for 1/8" OD tubing (in addition to the port which screws into the column endplate). The T-bore in the valve allows any 2 or all 3 ports to be connected together.

The 4-Port T-Bore Valve is also used for mixing, solvent selection, and flow diversion. It has 3 tubing fittings for 1/8" OD tubing (in addition to the port which screws into the column endplate). The valve connects each fluid port with one of those adjacent to it.

The Stream Splitting Valve combines a 3-Port T-Bore valve with a metering valve. This valve has 2 tubing fittings for 1/8" OD tubing (in addition to the port which screws into the column endplate). The T-bore in the valve allows any 2 or all 3 ports to be connected together. One of the tubing fittings also has a needle valve. This allows the fluid stream to be easily and reliably split between the 2 tubing fittings.

The only wetted material in these valves is PTFE, except for the stream splitting valve which also has a wetted Kel-F stem.

Multi-Port Valve Availability
Part No.DescriptionPrice
1243963-Port T-Bore Valve. Has 2 fittings for 1/8" OD tubing and screws into column endplate.427.00
1244024-Port T-Bore Valve. Has 3 fittings for 1/8" OD tubing and screws into column endplate.406.00
124438Stream Splitting Valve. Has 2 fittings for 1/8" OD tubing and screws into column endplate.597.00



Multifit Connectors are the connectors normally shipped on our columns. The standard connector on the small aqueous columns accepts 3/16" OD tubing; the large aqueous columns normally come with a multifit for 1/4" OD tubing. The standard connector on the small organic columns accepts 1/8" OD tubing; the large organic columns normally come with a multifit for 1/4" OD tubing.

These fittings are interchangeable, any size or style of fitting will fit any size or style of column.

The organic style of multifit connector uses a PTFE (white fluoropolymer) ferrule to grab the tubing. This makes them suitable for use with harder tubing made of polymers like PTFE or polyethylene. The aqueous style of multifit connector uses a soft fluoroelastomer O-ring to grab the tubing. This makes them suitable for use with softer tubing made of polymers like vinyl or silicone.

The only wetted material in these connectors is PTFE (a white, inert, fluoropolymer).

Multifit Connector Availability
Part No.DescriptionPrice
124380Aqueous style connector for 1/16" OD tubing.77.00
124384Aqueous style connector for 1/8" OD tubing.77.00
124391Aqueous style connector for 3/16" OD tubing.77.00
124390Aqueous style connector for 1/4" OD tubing.77.00
124487Organic style connector for 1/8" OD tubing.66.00
124489Organic style connector for 3/16" OD tubing.73.00
124488Organic style connector for 1/4" OD tubing.66.00
124491Organic style connector for 1/2" OD tubing. (Wetted materials include PTFE and Kel-F.)112.00



The Vent Port tubing adapter allows an additional fluid stream to be introduced to the column. The vent port tubing adapter screws into the upper endplate of a column, replacing the existing vent port plug.

The vent port tubing adapter has a compression fitting that accepts 1/8" OD tubing. It is made of polypropylene and thus suitable for use with most solvents. It is not for use with halogenated solvents.

Vent Port Fitting Availability
Part No.DescriptionPrice
124377Polypropylene vent Port tubing connector for 1/8" OD tubing.51.00



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